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Article

Female-Specific Susceptibility Locus in BOC and SEC16B are Associated with Adolescent Idiopathic Scoliosis.

Spine - 15 Nov 2021

Dai Zhicheng, Wang Yuwen, Wu Zhichong, Feng Zhenhua, Sun Xu, Qiu Yong, Cheng Jack Chun-Yiu, Xu Leilei, Zhu Zezhang

Abstract excerpt

STUDY DESIGN: A genetic case-control study. OBJECTIVES: To investigate whether the variants in BOC, SEC16B, and SH2D1B are sex-specifically and functionally associated with the susceptibility of adolescent idiopathic scoliosis (AIS) in Chinese Han population. SUMMARY OF BACKGROUND DATA: A recent genome-wide association study identified three female-specific susceptibility loci of AIS in Japanese population....

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PMID: 33958541
DOI: 10.1097/BRS.0000000000004098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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