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Article

Genetic disorders coupled to ROS deficiency.

Redox biology - 1 Dec 2015

O'Neill Sharon, Brault Julie, Stasia Marie-Jose, Knaus Ulla G

Abstract excerpt

Maintaining the redox balance between generation and elimination of reactive oxygen species (ROS) is critical for health. Disturbances such as continuously elevated ROS levels will result in oxidative stress and development of disease, but likewise, insufficient ROS production will be detrimental to health. Reduced or even complete loss of ROS generation originates mainly from inactivating variants in genes...

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Source

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Identifiers

PMID: 26210446
DOI: 10.1016/j.redox.2015.07.009
PMCID: PMC4550764

Genes

DUOX2
CYBA
CYBB
DUOXA2
NCF1
NCF2
NCF4
NOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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