Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APC:T1556fs and STK11 mutations in duodenal adenomas and adenocarcinomas.

Surgery today - 1 Aug 2018

Kojima Yohei, Ohtsuka Kouki, Ohnishi Hiroaki, Abe Nobutsugu, Furuse Junji, Watanabe Takashi, Sugiyama Masanori

Abstract excerpt

PURPOSE: Duodenal adenoma and adenocarcinoma (AC) are rare tumors, and few studies have examined their genetic features. We aimed to determine the key genetic changes in duodenal adenoma and AC, and to clarify the possible involvement of the adenoma-carcinoma sequence in duodenal tumor carcinogenesis. METHODS: Nineteen duodenal tumors collected by endoscopic mucosal resection or surgical resection were classified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Adenoma
Share to Adenomatous Polyposis Coli Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to AMP-Activated Protein Kinase Kinases

Share to Carcinogenesis

Share to Duodenal Neoplasms

Share to Neoplasm Staging

Share to Protein Serine-Threonine Kinases

Source

Identifiers

PMID: 29525853
DOI: 10.1007/s00595-018-1649-4

Genes

APC
HGD
STK11
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APC:T1556fs and STK11 mutations in duodenal adenomas and adenocarcinomas.PMID 29525853Read ↗

Genomic Profiling of Small Superficial Non-Ampullary Duodenal Epithelial TumorsSemantic proximity Read ↗

Whole-exome sequencing identified mutational profiles of high-grade colon adenomas.Semantic proximity Read ↗

Endoscopic indicators in patients with familial adenomatous polyposis undergoing duodenal resections – a nationwide Danish cohort study with long-term follow-upSemantic proximity Read ↗

Relationship between gene mutations and clinicopathological features in nonampullary duodenal epithelial tumors.Semantic proximity Read ↗

Mutational analysis by next generation sequencing of gastric type dysplasia occurring in hyperplastic polyps of the stomach: Mutations in gastric hyperplastic polyps.Semantic proximity Read ↗

Gene Expression Changes Accompanying the Duodenal Adenoma-Carcinoma Sequence in Familial Adenomatous PolyposisSemantic proximity Read ↗

Whole-exome sequencing of duodenal adenocarcinoma identifies recurrent Wnt/β-catenin signaling pathway mutations.Semantic proximity Read ↗

Gastric-Type Adenomas of the Nonampullary Duodenum: Reappraisal of Clinicopathological and Molecular Features and a Proposal for Novel Classification.Semantic proximity Read ↗

Cancer-Associated Mutations in Normal Colorectal Mucosa Adjacent to Sporadic Neoplasia.Semantic proximity Read ↗

Differential gene expression analysis and weighted gene co-expression network analysis reveal mechanism behind the development of duodenal carcinoma in familial adenomatous polyposisSemantic proximity Read ↗

Genetic alteration of colorectal adenoma-carcinoma sequence among gastric adenocarcinoma and dysplastic lesions in a patient with attenuated familial adenomatous polyposis.Semantic proximity Read ↗

The chronological sequence of somatic mutations in early gastric carcinogenesis inferred from multiregion sequencing of gastric adenomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.