Article
Genetic alteration of colorectal adenoma-carcinoma sequence among gastric adenocarcinoma and dysplastic lesions in a patient with attenuated familial adenomatous polyposis.
Molecular genetics & genomic medicine - 1 Sept 2020
Tanabe Hiroki, Moriichi Kentaro, Takahashi Keitaro, Ono Yusuke, Kobayashi Yu, Murakami Yuki, Iwama Takuya, Kunogi Takehito, Sasaki Takahiro, Ando Katsuyoshi, Ueno Nobuhiro, Kashima Shin, Takei Hidehiro, Mizukami Yusuke, Fujiya Mikihiro, Okumura Toshikatsu
Abstract excerpt
BACKGROUND: Familial adenomatous polyposis (FAP) is characterized by colorectal polyposis and adenocarcinoma that is frequently accompanied by extracolonic neoplasm. The risk of gastric carcinoma is increasing in Western FAP patients as well as Asian patients. METHODS: We report the case of an FAP patient with fundic gland polyposis who developed gastric adenocarcinoma and metachronous pyloric gland adenomas....
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