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Article

Clinical Application of Next-generation Sequencing for the Diagnosis of Lung Squamous Cell Carcinoma: Is It Primary or Secondary?

Internal medicine (Tokyo, Japan) - 15 May 2020

Aizawa Hiroaki, Karasaki Takahiro, Nagayama Kazuhiro, Shinozaki-Ushiku Aya, Aburatani Hiroyuki, Mano Hiroyuki, Nakajima Jun

Abstract excerpt

An 80-year-old man with a history of cutaneous squamous cell carcinoma (SCC) was referred to our department for a solitary lung nodule. The nodule was surgically resected and diagnosed as SCC. Because the lung lesion and a previous skin lesion showed similar histological findings, the origin of the lung tumor was uncertain. Next-generation sequencing using a targeted driver oncogene panel was applied for the...

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Share to Aged, 80 and over
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diagnosis, Differential

Share to High-Throughput Nucleotide Sequencing

Share to Lung Neoplasms

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Share to Tumor Suppressor Protein p53

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Identifiers

PMID: 32051379
DOI: 10.2169/internalmedicine.3682-19
PMCID: PMC7303454

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