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Article

Added Value of 50-Gene Panel Sequencing to Distinguish Multiple Primary Lung Cancers from Pulmonary Metastases: A Systematic Investigation.

The Journal of molecular diagnostics : JMD - 1 Jul 2018

Roepman Paul, Ten Heuvel Alexandra, Scheidel Karen C, Sprong Tobias, Heideman Danielle A M, Seldenrijk Kees A, Herder Gerarda J M, Kummer J Alain

Abstract excerpt

Differentiation between multiple primary lung cancers and pulmonary metastases (PM) has important implications in staging, prognosis, and treatment strategies. Clinical and immunohistopathologic criteria have been standardized; however, a substantial number of cases remain difficult to classify. Using next-generation sequencing, it is now possible to improve the classification of multiple lung cancer lesions....

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PMID: 29625247
DOI: 10.1016/j.jmoldx.2018.02.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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