Article
Beyond heritability: improving discoverability in imaging genetics.
Human molecular genetics - 1 May 2018
Fan Chun Chieh, Smeland Olav B, Schork Andrew J, Chen Chi-Hua, Holland Dominic, Lo Min-Tzu, Sundar V S, Frei Oleksandr, Jernigan Terry L, Andreassen Ole A, Dale Anders M
Abstract excerpt
Structural neuroimaging measures based on magnetic resonance imaging have been at the forefront of imaging genetics. Global efforts to ensure homogeneity of measurements across study sites have enabled large-scale imaging genetic projects, accumulating nearly 50K samples for genome-wide association studies (GWAS). However, not many novel genetic variants have been identified by these GWAS, despite the high...
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