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Article

Impact of CYP2C19 polymorphism in prognosis of minor stroke or TIA patients with declined eGFR on dual antiplatelet therapy: CHANCE substudy.

The pharmacogenomics journal - 1 Dec 2018

Wu Yu, Zhou Yilun, Pan Yuesong, Zhao Xingquan, Liu Liping, Wang David, Wang Chunxue, Li Hao, Johnston S Claiborne, Meng Xia, Wang Yilong, Wang Yongjun

Abstract excerpt

Clopidogrel resistance is prevalent in chronic kidney disease (CKD) patients. Genetic polymorphism is considered to be the most important factor that influences clopidogrel resistance. Limited data exist as to the role of pharmacogenetics in prognosis of stroke patients with impaired renal function on clopidogrel. We sought to explore whether decreased kidney function alters the association between CYP2C19...

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Identifiers

PMID: 29520080
DOI: 10.1038/s41397-018-0018-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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