Article
Effect of CYP2C19*2 and *3 on clinical outcome in ischemic stroke patients treated with clopidogrel.
Journal of the neurological sciences - 15 Oct 2016
Wang Yingting, Cai Huan, Zhou Guoqing, Zhang Zhizhong, Liu Xinfeng
Abstract excerpt
BACKGROUND: Despite clopidogrel has been widely applied to patients with ischemic stroke combined with aspirin, decreased metabolic activation of clopidogrel still occurs because of genetic variations in CYP2C19. METHODS: Three hundred twenty-one patients completed a genetic test for CYP2C19 loss of function (LOF) alleles in hospital. Cox regression models were used to assess the relationship between CYP2C19...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
