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Article

Age-dependent association of CYP2C19 polymorphisms with clinical outcome of clopidogrel therapy in minor stroke patients with large-artery atherosclerosis.

European journal of clinical pharmacology - 1 Sept 2020

Wang Dapeng, Li Lingjie, Jiang Jianhua, Zhang Quanquan, Liu Meirong, Liu Yang, Zhao Hongru, Fang Qi

Abstract excerpt

PURPOSE: Previous studies on the association between CYP2C19 polymorphisms and therapeutic outcome of clopidogrel in stroke patients are inconclusive. We aimed to investigate the impact of CYP2C19 polymorphisms on therapeutic efficacy of clopidogrel in both young and old minor stroke patients associated with large-artery atherosclerosis (LAA). METHODS: A total of 510 eligible patients were enrolled between April...

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Identifiers

PMID: 32504182
DOI: 10.1007/s00228-020-02905-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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