Article
Cleavage site of Newcastle disease virus determines viral fitness in persistent infection cells.
Veterinary microbiology - 1 Mar 2018
Liu Haijin, Servan de Almeida Renata, Gil Patricia, Albina Emmanuel
Abstract excerpt
Newcastle disease, caused by infection with virulent strains of Newcastle disease virus (NDV), poses a risk for the poultry industry. The virulence of NDV is mainly determined by the cleavage site of F protein. Lentogenic NDV can become velogenic after passages in SPF chicken brain and air sac based on some strains isolated from water birds, because the proportion of virulent-related strains gradually increases....
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