Article
Evolution of Newcastle Disease Virus Quasispecies Diversity and Enhanced Virulence after Passage through Chicken Air Sacs.
Journal of virology - 15 Feb 2016
Meng Chunchun, Qiu Xusheng, Yu Shengqing, Li Chuanfeng, Sun Yingjie, Chen Zongyan, Liu Kaichun, Zhang Xiangle, Tan Lei, Song Cuiping, Liu Guangqing, Ding Chan
Abstract excerpt
UNLABELLED: It has been reported that lentogenic Newcastle disease virus (NDV) isolates have the potential to become velogenic after their transmission and circulation in chickens, but the underlying mechanism is unclear. In this study, a highly velogenic NDV variant, JS10-A10, was generated from the duck-origin lentogenic isolate JS10 through 10 consecutive passages in chicken air sacs. The velogenic properties...
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