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Article

Unravelling the Effects of the Mutation m.3571insC/MT-ND1 on Respiratory Complexes Structural Organization.

International journal of molecular sciences - 7 Mar 2018

Iommarini Luisa, Ghelli Anna, Tropeano Concetta Valentina, Kurelac Ivana, Leone Giulia, Vidoni Sara, Lombes Anne, Zeviani Massimo, Gasparre Giuseppe, Porcelli Anna Maria

Abstract excerpt

Mammalian respiratory complex I (CI) biogenesis requires both nuclear and mitochondria-encoded proteins and is mostly organized in respiratory supercomplexes. Among the CI proteins encoded by the mitochondrial DNA, NADH-ubiquinone oxidoreductase chain 1 (ND1) is a core subunit, evolutionary conserved from bacteria to mammals. Recently, ND1 has been recognized as a pivotal subunit in maintaining the structural and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29518970
DOI: 10.3390/ijms19030764
PMCID: PMC5877625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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