Article
TREM2 and Amyloid Beta: A Love-Hate Relationship.
Neuron - 7 Mar 2018
Udeochu Joe, Sayed Faten A, Gan Li
Abstract excerpt
Mutations in TREM2 increase risk for late-onset AD. In this issue of Neuron, Zhao et al. (2018) show that TREM2 binds Aβ to enhance its clearance and Lee et al. (2018) demonstrate that human TREM2 expression in AD mice ameliorates Aβ-associated deficits.
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