A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus.

doi:10.1136/ard.2009.115535

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Article

A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus.

Annals of the rheumatic diseases - 1 May 2010

Svenungsson Elisabet, Gustafsson Johanna, Leonard Dag, Sandling Johanna, Gunnarsson Iva, Nordmark Gunnel, Jönsen Andreas, Bengtsson Anders A, Sturfelt Gunnar, Rantapää-Dahlqvist Solbritt, Elvin Kerstin, Sundin Ulf, Garnier Sophie, Simard Julia F, Sigurdsson Snaevar, Padyukov Leonid, Syvänen Ann-Christine, Rönnblom Lars

Abstract excerpt

OBJECTIVE: To investigate whether the risk allele for systemic lupus erythematosus (SLE) in the signal transducer and activator of transcription factor 4 (STAT4) gene, defined by the single nucleotide polymorphism (SNP) rs10181656(G), is associated with vascular events and/or presence of prothrombotic anti-phospholipid antibodies (aPL) in patients with SLE. METHODS: Two independent groups of unrelated patients...

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PMID: 19762360
DOI: 10.1136/ard.2009.115535

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STAT4

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