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Article

Protein kinase C: perfectly balanced.

Critical reviews in biochemistry and molecular biology - 1 Apr 2018

Newton Alexandra C

Abstract excerpt

Protein kinase C (PKC) isozymes belong to a family of Ser/Thr kinases whose activity is governed by reversible release of an autoinhibitory pseudosubstrate. For conventional and novel isozymes, this is effected by binding the lipid second messenger, diacylglycerol, but for atypical PKC isozymes, this is effected by binding protein scaffolds. PKC shot into the limelight following the discovery in the 1980s that...

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Identifiers

PMID: 29513138
DOI: 10.1080/10409238.2018.1442408
PMCID: PMC5901981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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