Article
Pseudomonas aeruginosa infection alters the macrophage phenotype switching process during wound healing in diabetic mice.
Cell biology international - 1 Jul 2018
Chen Sinuo, Li Renren, Cheng Chun, Xu Jing-Ying, Jin Caixia, Gao Furong, Wang Juan, Zhang Jieping, Zhang Jingfa, Wang Hong, Lu Lixia, Xu Guo-Tong, Tian Haibin
Abstract excerpt
Macrophages play critical roles in wound healing process. They switch from "classically activated" (M1) phenotype in the early inflammatory phase to "alternatively activated" (M2) phenotype in the later healing phase. However, the dynamic process of macrophage phenotype switching in diabetic wounds burdened with bacteria is unclear. In this report, Pseudomonas aeruginosa, frequently detected in diabetic foot...
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