Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophage PPARγ and impaired wound healing in type 2 diabetes.

The Journal of pathology - 1 Aug 2015

Mirza Rita E, Fang Milie M, Novak Margaret L, Urao Norifumi, Sui Audrey, Ennis William J, Koh Timothy J

Abstract excerpt

Macrophages undergo a transition from pro-inflammatory to healing-associated phenotypes that is critical for efficient wound healing. However, the regulation of this transition during normal and impaired healing remains to be elucidated. In our studies, the switch in macrophage phenotypes during skin wound healing was associated with up-regulation of the peroxisome proliferator-activated receptor (PPAR)γ and its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Wound Healing
Share to Administration, Cutaneous
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-1beta

Share to PPAR gamma

Share to Rosiglitazone

Share to Thiazolidinediones

Source

Open in PubMed Open full text

Identifiers

PMID: 25875529
DOI: 10.1002/path.4548
PMCID: PMC4509817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophage PPARγ and impaired wound healing in type 2 diabetes.PMID 25875529Read ↗

Macrophages as a therapeutic target to promote diabetic wound healing.Semantic proximity Read ↗

The physiological phenomenon and regulation of macrophage polarization in diabetic wound.Semantic proximity Read ↗

Macrophage Phenotypes in Normal and Diabetic Wound Healing and Therapeutic Interventions.Semantic proximity Read ↗

Insulin promotes macrophage phenotype transition through PI3K/Akt and PPAR-γ signaling during diabetic wound healing.Semantic proximity Read ↗

Macrophage polarization and diabetic wound healing.Semantic proximity Read ↗

Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound HealingSemantic proximity Read ↗

Uncovering Sex-Related Differences in Skin Macrophage Polarization During Wound Healing in Diabetic Mice.Semantic proximity Read ↗

Dysfunctional crosstalk between macrophages and fibroblasts under LPS-infected and hyperglycemic environment in diabetic woundsSemantic proximity Read ↗

Macrophage and Neutrophil Dysfunction in Diabetic WoundsSemantic proximity Read ↗

Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound RepairSemantic proximity Read ↗

Wound Macrophages as Key Regulators of RepairSemantic proximity Read ↗

Diabetes-impaired wound healing and altered macrophage activation: a possible pathophysiologic correlation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.