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Article

The phenotype and functional alterations of macrophages in mice with hyperglycemia for long term.

Journal of cellular physiology - 1 Apr 2012

Sun Chenming, Sun Lina, Ma Haixia, Peng Jianxia, Zhen Yu, Duan Kaizhong, Liu Guangwei, Ding Wenjun, Zhao Yong

Abstract excerpt

Abnormal immunity and its related complications are the major causes of mortality and morbidity in diabetes patients. Macrophages, as one of the important innate cells, play pivotal roles in controlling immune homeostasis, immunity, and tolerance. The effects of hyperglycemia on the function of macrophages in hosts remain to be determined. Here we used mice with streptozotocin (STZ)-induced diabetes for long term...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21678423
DOI: 10.1002/jcp.22891

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TNF

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