Article
Genetic Variations, Exposure to Persistent Organic Pollutants and Breast Cancer Risk - A Greenlandic Case-Control Study.
Basic & clinical pharmacology & toxicology - 1 Sept 2018
Wielsøe Maria, Eiberg Hans, Ghisari Mandana, Kern Peder, Lind Ole, Bonefeld-Jørgensen Eva Cecilie
Abstract excerpt
This study investigated the effects of single nucleotide polymorphisms (SNPs) in xenobiotic and steroid hormone-metabolizing genes in relation to breast cancer risk and explored possible effect modifications on persistent organic pollutants (POPs) and breast cancer associations. The study also assessed effects of Greenlandic BRCA1 founder mutations. Greenlandic Inuit women (77 cases and 84 controls) were...
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