Article
Blood and tissue levels of persistent organic pollutants and genetic susceptibility in patients with breast cancer.
Environmental toxicology and pharmacology - 1 Jun 2024
Onat İlgen, Kocagöz Rasih, Öz Merve Demirbügen, Yeniay Levent, Tiftikçioğlu Yiğit Özer, Zekioğlu Osman, Serin Gürdeniz, Özdemir Murat, Gür Ersin, Süzen Halit Sinan, Orhan Hilmi
Abstract excerpt
We investigated possible associations between the internal concentrations of POPs and correlations between blood and tumor tissue concentrations in patients who underwent surgery for breast cancer and breast reduction as controls. Genetic variations in CYP1A1, GSTP1, GSTM1, and GSTT1 and hOGG1 were evaluated to determine whether they represent risk factors for breast cancer. Certain POPs have been found to be...
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