Article
Complex genetic interactions of novel Suppressor of Hairless alleles deficient in co-repressor binding.
PloS one - 1 Jan 2018
Preiss Anette, Nagel Anja C, Praxenthaler Heiko, Maier Dieter
Abstract excerpt
Throughout the animal kingdom, the Notch signalling pathway allows cells to acquire diversified cell fates. Notch signals are translated into activation of Notch target genes by CSL transcription factors. In the absence of Notch signals, CSL together with co-repressors functions as a transcriptional repressor. In Drosophila, repression of Notch target genes involves the CSL homologue Suppressor of Hairless...
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