Article
Cardiac sympathetic denervation in symptomatic and asymptomatic carriers of the E46K mutation in the α synuclein gene.
Parkinsonism & related disorders - 1 Jan 2013
Tijero Beatriz, Gómez-Esteban Juan Carlos, Lezcano Elena, Fernández-González Carmen, Somme Johanne, Llorens Verónica, Martínez Ana, Ruiz-Martínez Javier, Foncea Nerea, Escalza Inés, Berganzo Koldo, Aniel-Quiroga M A, Ruiz Verónica, Terán Nuria, Kaufmann Horacio, Zarranz Juan Jose
Abstract excerpt
OBJECTIVE: The aim of this study was to analyze autonomic function and cardiac sympathetic innervation in symptomatic and asymptomatic carriers of the E46K alpha-synuclein gene (SNCA) mutation. PATIENTS AND METHODS: Autonomic function tests were performed in six patients, four of whom were symptomatic carriers (ages: 46, 59, 52 and 28-years) and two who were asymptomatic carriers (ages: 52 and 29 years). Autopsy...
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