Article
Variation in the calpain-10 gene is not associated with gestational diabetes mellitus.
Scandinavian journal of clinical and laboratory investigation - 1 Jan 2014
Neuhaus Thomas, Graf Christian, Stier Sebastian, Knapp Michael, Grunewald Elisabeth, Ko Yon-Dschun, Sorger Marianne
Abstract excerpt
BACKGROUND: In several large studies an association between certain single-nucleotide polymorphisms (SNP) of the calpain-10 gene (CAPN10) with type 2 diabetes mellitus (T2D) has been identified. Since T2D and gestational diabetes mellitus (GDM) seem to be linked pathophysiologically, we examined the frequencies of CAPN10-polymorphisms in women with GDM. METHODS: By using real-time PCR assisted melting curve...
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