Article
Genetically elevated gamma-glutamyltransferase and Alzheimer's disease.
Experimental gerontology - 1 Jun 2018
Kunutsor Setor K, Laukkanen Jari A, Burgess Stephen
Abstract excerpt
Observational epidemiological evidence supports a linear and independent association between serum gamma-glutamyltransferase (GGT) concentrations and the risk of Alzheimer's disease (AD). However, the causality of this association has not been previously investigated. We sought to assess the causal nature of this association using a Mendelian randomization (MR) approach. Using inverse-variance weighted MR...
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