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Article

Gamma-glutamyltransferase levels, prediabetes and type 2 diabetes: a Mendelian randomization study.

International journal of epidemiology - 1 Oct 2017

Nano Jana, Muka Taulant, Ligthart Symen, Hofman Albert, Darwish Murad Sarwa, Janssen Harry L A, Franco Oscar H, Dehghan Abbas

Abstract excerpt

Background: High levels of serum gamma-glutamyltransferase (GGT) are associated with increased risk of prediabetes and type 2 diabetes in observational studies. It is unclear whether this relationship is causal, arises from residual confounding or is a consequence of reverse causation. Methods: We used data from a prospective population-based cohort study, compromising 8611 individuals without diabetes at...

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PMID: 28338987
DOI: 10.1093/ije/dyx006

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