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A facile forward-genetic screen forArabidopsisautophagy mutants reveals twenty-one loss-of-function mutations disrupting sixATGgenes

8 Feb 2019

Abstract excerpt

Macroautophagy is a process through which eukaryotic cells degrade large substrates including organelles, protein aggregates, and invading pathogens. Over 40 autophagy-related (ATG) genes have been identified through forward-genetic screens in yeast. Although homology-based analyses have identified conserved ATG genes in plants, only a few atg mutants have emerged from forward-genetic screens in Arabidopsis...

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PMID: 30734619
DOI: 10.1080/15548627.2019.1569915

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