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Article

Catechol-O-methyltransferase Val158Met polymorphism associates with affect and cortisol levels in women.

Brain and behavior - 1 Feb 2018

Hill Lauren D, Lorenzetti Margaret S, Lyle Sarah M, Fins Ana I, Tartar Aurélien, Tartar Jaime L

Abstract excerpt

Introduction: We tested the extent to which the catechol-O-methyltransferase (COMT) Val158Met polymorphism is associated with affective state and evening cortisol levels. We limited our study to women as previous research suggests that the link between COMT genotype and psychological health is entangled by sex differences. Materials and Methods: The participants were assessed on measures of anxiety, mood...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29484256
DOI: 10.1002/brb3.883
PMCID: PMC5822566

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

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Catechol-O-methyltransferase Val158Met polymorphism associates with affect and cortisol levels in women.PMID 29484256Read ↗

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Stress-related methylation of the catechol-O-methyltransferase Val 158 allele predicts human prefrontal cognition and activity.Semantic proximity Read ↗

Catechol-O-methyltransferase val158met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex.Semantic proximity Read ↗

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