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Article

COMT Val(108/158)Met polymorphism effects on emotional brain function and negativity bias.

NeuroImage - 15 Nov 2010

Williams Leanne M, Gatt Justine M, Grieve Stuart M, Dobson-Stone Carol, Paul Robert H, Gordon Evian, Schofield Peter R

Abstract excerpt

Biases toward processing negative versus positive information vary as a function of level of awareness, and are modulated by monoamines. Excessive biases are associated with individual differences in mood and emotional stability, and emotional disorder. Here, we examined the impact of the catechol-O-methyltransferase (COMT) Val(108/158)Met polymorphism, involved in dopamine and norepinephrine catabolism, on both...

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Source

Identifiers

PMID: 20139013
DOI: 10.1016/j.neuroimage.2010.01.084

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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