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Article

Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Del-Aguila Jorge L, Fernández Maria Victoria, Schindler Suzanne, Ibanez Laura, Deming Yuetiva, Ma Shengmei, Saef Ben, Black Kathleen, Budde John, Norton Joanne, Chasse Rachel, Harari Oscar, Goate Alison, Xiong Chengjie, Morris John C, Cruchaga Carlos

Abstract excerpt

Many genetic studies for Alzheimer's disease (AD) have been focused on the identification of common genetic variants associated with AD risk and not on other aspects of the disease, such as age at onset or rate of dementia progression. There are multiple approaches to untangling the genetic architecture of these phenotypes. We hypothesized that the genetic architecture of rate of progression is different than the...

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Source

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Identifiers

PMID: 29480181
DOI: 10.3233/JAD-170834
PMCID: PMC5989565

Genes

TREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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