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Article

The role of the folate pathway in pancreatic cancer risk.

PloS one - 1 Jan 2018

Chittiboyina Shirisha, Chen Zhongxue, Chiorean E Gabriela, Kamendulis Lisa M, Hocevar Barbara A

Abstract excerpt

BACKGROUND: Pancreatic cancer is the third leading cause of cancer related deaths in the United States. Several dietary factors have been identified that modify pancreatic cancer risk, including low folate levels. In addition to nutrition and lifestyle determinants, folate status may be influenced by genetic factors such as single nucleotide polymorphisms (SNPs). In the present study, we investigated the...

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Identifiers

PMID: 29474406
DOI: 10.1371/journal.pone.0193298
PMCID: PMC5825090

Genes

CHDH
MTHFR
MTR
PEMT
SHMT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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