Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Aug 2005

Wang Li, Miao Xiaoping, Tan Wen, Lu Xinghua, Zhao Ping, Zhao Xiaohang, Shan Yi, Li Hui, Lin Dongxin

Abstract excerpt

BACKGROUND & AIMS: Human pancreatic cancer might be associated with folate deficiency and impaired metabolism. We tested this hypothesis by examining the contribution of functional polymorphisms in methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase (TS) to risk of cancer. METHOD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Logistic Models

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Pancreatic Neoplasms

Share to Smoking

Share to Thymidylate Synthase

Source

Identifiers

PMID: 16234002
DOI: 10.1016/s1542-3565(05)00156-4

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16234002-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer.PMID 16234002Read ↗

5,10-Methylenetetrahydrofolate reductase polymorphisms and the risk of pancreatic cancer.Semantic proximity Read ↗

Alcohol drinking and one-carbon metabolism-related gene polymorphisms on pancreatic cancer risk.Semantic proximity Read ↗

The role of the folate pathway in pancreatic cancer risk.Semantic proximity Read ↗

Associations between polymorphisms in folate-metabolizing genes and pancreatic cancer risk in Japanese subjects.Semantic proximity Read ↗

MTHFR C677T polymorphism and pancreatic cancer risk: a meta-analysis.Semantic proximity Read ↗

[Study on the relations between genetic polymorphisms in methylenetetrahydrofolate reductase, methionine synthase and the risk of pancreatic cancer].Semantic proximity Read ↗

Association of MTHFR gene polymorphisms with pancreatic cancer: meta-analysis of 17 case-control studies.Semantic proximity Read ↗

Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes.Semantic proximity Read ↗

MTHFR polymorphisms and pancreatic cancer risk: lack of evidence from a meta-analysis.Semantic proximity Read ↗

His595Tyr polymorphism in the methionine synthase reductase (MTRR) gene is associated with pancreatic cancer risk.Semantic proximity Read ↗

Polymorphisms and pancreatic cancer risk: a meta-analysis.Semantic proximity Read ↗

Molecular epidemiology of pancreatic cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.