Article
Association of MTHFR gene polymorphisms with pancreatic cancer: meta-analysis of 17 case-control studies.
International journal of clinical oncology - 1 Feb 2020
Nie Fangfang, Yu Mingli, Zhang Kaili, Yang Luping, Zhang Qian, Liu Shan, Liu Mengwei, Shang Mengke, Zeng Fanxin, Liu Wanyang
Abstract excerpt
BACKGROUND: Pancreatic cancer (PC) is a seriously malignant tumor with a low 5-year survival rate. The relationship between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and PC has been reported by several studies. However, the results were controversial. Thus, we conducted a meta-analysis to summarize available data on MTHFR gene and PC. METHODS: We searched PubMed, Embase, Web of Science,...
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