Article
Associations between polymorphisms in folate-metabolizing genes and pancreatic cancer risk in Japanese subjects.
BMC gastroenterology - 29 Jul 2016
Nakao Haruhisa, Wakai Kenji, Ishii Norimitsu, Kobayashi Yuji, Ito Kiyoaki, Yoneda Masashi, Mori Mitsuru, Nojima Masanori, Kimura Yasutoshi, Endo Takao, Matsuyama Masato, Ishii Hiroshi, Ueno Makoto, Kuruma Sawako, Egawa Naoto, Matsuo Keitaro, Hosono Satoyo, Ohkawa Shinichi, Nakamura Kozue, Tamakoshi Akiko, Takahashi Mami, Shimada Kazuaki, Nishiyama Takeshi, Kikuchi Shogo, Lin Yingsong
Abstract excerpt
BACKGROUND: Evidence supporting the associations between folate metabolizing gene polymorphisms and pancreatic cancer has been inconclusive. We examined their associations in a case-control study of Japanese subjects. METHODS: Our case-control study involved 360 newly diagnosed pancreatic cancer cases and 400 frequency-matched, non-cancer control subjects. We genotyped four folate metabolizing gene polymorphisms,...
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