Article
Validation of a Customized Bioinformatics Pipeline for a Clinical Next-Generation Sequencing Test Targeting Solid Tumor-Associated Variants.
The Journal of molecular diagnostics : JMD - 1 May 2018
Schneider Thomas, Smith Geoffrey H, Rossi Michael R, Hill Charles E, Zhang Linsheng
Abstract excerpt
Bioinformatic analysis is an integral and critical part of clinical next-generation sequencing. It is especially challenging for some pipelines to consistently identify insertions and deletions. We present the validation of an open source tumor amplicon pipeline (OTA-pipeline) for clinical next-generation sequencing targeting solid tumor-associated variants. Raw data generated from 557 TruSight Tumor 26 samples...
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