Article
Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing.
Pathology, research and practice - 1 Jul 2018
Zhong Qing, Wagner Ulrich, Kurt Henriette, Molinari Francesca, Cathomas Gieri, Komminoth Paul, Barman-Aksözen Jasmin, Schneider-Yin Xiaoye, Rey Jean-Philippe, Vassella Erik, Rogel Uwe, Diebold Joachim, McKee Thomas, Jochum Wolfram, Kashofer Karl, Hofman Paul, Zischka Melanie, Moch Holger, Rechsteiner Markus, Wild Peter J
Abstract excerpt
Next-generation sequencing (NGS) enables parallel analysis of multiple genomic targets. The increasing demand for NGS-based multiplexed molecular diagnostics requires standardized protocols and recommendations to ensure reproducibility and accuracy of test results for routine clinical decision making. However, the lack of clinical NGS data from multi-laboratory tests and the absence of inter-laboratory...
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