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Article

Anaplastic carcinoma of the ovary: A single-institution experience and molecular analysis.

Gynecologic oncology - 1 Apr 2025

Sullivan Mackenzie W, Chui M Herman, Selenica Pier, Long Roche Kara, Sonoda Yukio, Grisham Rachel N, Kyi Chrisann, Momeni-Boroujeni Amir, Abu-Rustum Nadeem R, Weigelt Britta, O'Cearbhaill Roisin E

Abstract excerpt

OBJECTIVE: We describe a tertiary referral center's experience with anaplastic ovarian carcinoma and characterize the genetic landscape of these rare tumors. METHODS: Anaplastic ovarian carcinomas were retrospectively identified from institutional databases from 2013 to 2023. Clinical data and survival outcomes were abstracted from the electronic medical record. Molecular data were obtained from clinical...

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PMID: 40112666
DOI: 10.1016/j.ygyno.2025.03.021
PMCID: PMC12010851

Genes

CDKN2A
KRAS
TP53

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