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Article

Fetal Genotype and Maternal Glucose Have Independent and Additive Effects on Birth Weight.

Diabetes - 1 May 2018

Hughes Alice E, Nodzenski Michael, Beaumont Robin N, Talbot Octavious, Shields Beverley M, Scholtens Denise M, Knight Bridget A, Lowe William L, Hattersley Andrew T, Freathy Rachel M

Abstract excerpt

Maternal glycemia is a key determinant of birth weight, but recent large-scale genome-wide association studies demonstrated an important contribution of fetal genetics. It is not known whether fetal genotype modifies the impact of maternal glycemia or whether it acts through insulin-mediated growth. We tested the effects of maternal fasting plasma glucose (FPG) and a fetal genetic score for birth weight on birth...

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Identifiers

PMID: 29463506
DOI: 10.2337/db17-1188
PMCID: PMC5910006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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