Article
An expanded enzyme toolbox for production of cis, cis-muconic acid and other shikimate pathway derivatives in Saccharomyces cerevisiae.
FEMS yeast research - 1 Mar 2018
Brückner Christine, Oreb Mislav, Kunze Gotthard, Boles Eckhard, Tripp Joanna
Abstract excerpt
A wide range of commercially relevant aromatic chemicals can be synthesized via the shikimic acid pathway. Thus, this pathway has been the target of diverse metabolic engineering strategies. In the present work, an optimized yeast strain for production of the shikimic acid pathway intermediate 3-dehydroshikimate (3-DHS) was generated, which is a precursor for the production of the valuable compounds cis,...
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