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Article

Production of 2,3-butanediol by engineered Saccharomyces cerevisiae.

Bioresource technology - 1 Oct 2013

Kim Soo-Jung, Seo Seung-Oh, Jin Yong-Su, Seo Jin-Ho

Abstract excerpt

In order to produce 2,3-butanediol (2,3-BD) with a high titer, it is necessary to engineer Saccharomyces cerevisiae by deleting the competing pathway and overexpressing the 2,3-BD biosynthetic pathway. A pyruvate decarboxylase (Pdc)-deficient mutant was constructed and evolved for rapid glucose consumption without ethanol production. Genome re-sequencing of the evolved strain (SOS4) revealed a point mutation...

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Source

Identifiers

PMID: 23941711
DOI: 10.1016/j.biortech.2013.07.081

Genes

BDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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