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Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes

11 Jun 2015

Abstract excerpt

We tested the hypothesis that alterations in the intestinal microbiota are linked with the progression of type 1 diabetes (T1D). Herein, we present results from a study performed in subjects with islet autoimmunity living in the U.S. High-throughput sequencing of bacterial 16S rRNA genes and adjustment for sex, age, autoantibody presence, and HLA indicated that the gut microbiomes of seropositive subjects...

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PMID: 26068542
DOI: 10.2337/db14-1847

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