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Beyond genetics. Influence of dietary factors and gut microbiota on type 1 diabetes

18 Apr 2014

Abstract excerpt

Type 1 diabetes (T1D) is an autoimmune disease ultimately leading to destruction of insulin secreting β-cells in the pancreas. Genetic susceptibility plays an important role in T1D etiology, but even mono-zygotic twins only have a concordance rate of around 50%, underlining that other factors than purely genetic are involved in disease development. Here we review the influence of dietary and environmental factors...

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PMID: 24746688
DOI: 10.1016/j.febslet.2014.04.010

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