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Article

Non-genomic effects of nuclear receptors: insights from the anucleate platelet

13 Feb 2018

Abstract excerpt

Nuclear receptors (NRs) have the ability to elicit two different kinds of responses, genomic and non-genomic. Although genomic responses control gene expression by influencing the rate of transcription, non-genomic effects occur rapidly and independently of transcriptional regulation. Due to their anucleate nature and mechanistically well-characterized and rapid responses, platelets provide a model system for the...

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PMID: 29452349
DOI: 10.1093/cvr/cvy044

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