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Article

The Role of Cytochromes P450 in Infection.

Frontiers in immunology - 1 Jan 2018

Stavropoulou Elisavet, Pircalabioru Gratiela G, Bezirtzoglou Eugenia

Abstract excerpt

Cytochromes are expressed in many different tissues of the human body. They are found mostly in intestinal and hepatic tissues. Cytochromes P450 (CYPs) are enzymes that oxidize substances using iron and are able to metabolize a large variety of xenobiotic substances. CYP enzymes are linked to a wide array of reactions including and O-dealkylation, S-oxidation, epoxidation, and hydroxylation. The activity of the...

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Identifiers

PMID: 29445375
DOI: 10.3389/fimmu.2018.00089
PMCID: PMC5797775

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