Article
findGSE: estimating genome size variation within human and Arabidopsis using k-mer frequencies.
Bioinformatics (Oxford, England) - 15 Feb 2018
Sun Hequan, Ding Jia, Piednoël Mathieu, Schneeberger Korbinian
Abstract excerpt
Motivation: Analyzing k-mer frequencies in whole-genome sequencing data is becoming a common method for estimating genome size (GS). However, it remains uninvestigated how accurate the method is, especially if it can capture intra-species GS variation. Results: We present findGSE, which fits skew normal distributions to k-mer frequencies to estimate GS. findGSE outperformed existing tools in an extensive...
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