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Article

Whole-genome duplication increases genetic diversity and load in outcrossing Arabidopsis arenosa.

Proceedings of the National Academy of Sciences of the United States of America - 5 Aug 2025

Vlček Jakub, Hämälä Tuomas, Vives Cobo Cristina, Curran Emma, Šrámková Gabriela, Slotte Tanja, Schmickl Roswitha, Yant Levi, Kolář Filip

Abstract excerpt

Genetic variation underpins evolutionary change, but mutation accumulation increases genetic load. Various factors affect the extent of load, such as population size and breeding system, but other important determinants remain unexplored. In particular, whole-genome duplication (WGD)-a pervasive macromutation occurring broadly across Eukaryotes-remains poorly understood in terms of its impact on neutral and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40737318
DOI: 10.1073/pnas.2501739122
PMCID: PMC12337351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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