Article
Correlation between global methylation level of peripheral blood leukocytes and serum C reactive protein level modified by MTHFR polymorphism: a cross-sectional study.
BMC cancer - 13 Feb 2018
Nojima Masanori, Iwasaki Motoki, Kasuga Yoshio, Yokoyama Shiro, Onuma Hiroshi, Nishimura Hideki, Kusama Ritsu, Yoshida Teruhiko, Tsugane Shoichiro
Abstract excerpt
BACKGROUND: Chronic inflammatory conditions are associated with higher tumor incidence through epigenetic and genetic alterations. Here, we focused on an association between an inflammation marker, C-reactive-protein (CRP), and global DNA methylation levels of peripheral blood leukocytes. METHODS: The subjects were 384 healthy Japanese women enrolled as the control group of a case-control study for breast cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.