Article
Association between global leukocyte DNA methylation and cardiovascular risk in postmenopausal women.
BMC medical genetics - 10 Oct 2016
Ramos Ramon Bossardi, Fabris Vitor, Lecke Sheila Bunecker, Maturana Maria Augusta, Spritzer Poli Mara
Abstract excerpt
BACKGROUND: Genetic studies to date have not provided satisfactory evidence regarding risk polymorphisms for cardiovascular disease (CVD). Conversely, epigenetic mechanisms, including DNA methylation, seem to influence the risk of CVD and related conditions. Because postmenopausal women experience an increase in CVD, we set out to determine whether global DNA methylation was associated with cardiovascular risk in...
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