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Article

Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein.

PLoS neglected tropical diseases - 1 Feb 2018

Budigi Yadunanda, Ong Eugenia Z, Robinson Luke N, Ong Li Ching, Rowley Kirk J, Winnett Alexander, Tan Hwee Cheng, Hobbie Sven, Shriver Zachary, Babcock Gregory J, Alonso Sylvie, Ooi Eng Eong

Abstract excerpt

Dengue virus (DENV) infection imposes enormous health and economic burden worldwide with no approved treatment. Several small molecules, including lovastatin, celgosivir, balapiravir and chloroquine have been tested for potential anti-dengue activity in clinical trials; none of these have demonstrated a protective effect. Recently, based on identification and characterization of cross-serotype neutralizing...

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Identifiers

PMID: 29425203
DOI: 10.1371/journal.pntd.0006209
PMCID: PMC5823465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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