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Article

Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention.

Proceedings of the National Academy of Sciences of the United States of America - 29 May 2007

Goncalvez Ana P, Engle Ronald E, St Claire Marisa, Purcell Robert H, Lai Ching-Juh

Abstract excerpt

Infection with dengue virus (DENV) or any other flavivirus induces cross-reactive, but weakly neutralizing or nonneutralizing, antibodies that recognize epitopes involving the fusion peptide in the envelope glycoprotein. Humanized mAb IgG 1A5, derived from a chimpanzee, shares properties of cross...

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Identifiers

PMID: 17517625
DOI: 10.1073/pnas.0703498104
PMCID: PMC1868655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17517625-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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